Last update
5/6/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 2 Reviews
8.5
Supplement Facts
Serving Size: 1 tsp (1.9 g)
Amount Per Serving
%DV
Calories
5
Total Carbohydrates
1 g
<1%*
Dietary Fiber
<1 g
3%
Calcium
71 mg
5%
Valerian, cut (root)
1.9 g
**
Top Medical Research Studies
9
We examined the effects of embelin, a compound derived from the dried berries of Embelia ribes, on cholesterol levels by focusing on its relationship with calcium in liver cells. Our analysis showed that embelin treatment aids in regulating cholesterol metabolism by influencing key proteins associated with cholesterol clearance.
The study highlighted how embelin can elevate calcium levels within the endoplasmic reticulum (ER), which is essential for proper cellular function. By increasing calcium, we observed a decrease in the activity of a protein known as PCSK9, which typically hinders the liver's ability to remove low-density lipoprotein (LDL) cholesterol from circulation.
By regulating the levels of SREBP2, another protein linked to cholesterol control, embelin ultimately enhances the liver's capacity to clear LDL from the bloodstream. This mechanism reveals that calcium plays an important role, particularly in how embelin mediates cholesterol levels through its effects on proteins involved in cholesterol metabolism.
Overall, the findings suggest that embelin may offer a natural avenue for improving cholesterol management, particularly in the context of cardiovascular health.
The study highlighted how embelin can elevate calcium levels within the endoplasmic reticulum (ER), which is essential for proper cellular function. By increasing calcium, we observed a decrease in the activity of a protein known as PCSK9, which typically hinders the liver's ability to remove low-density lipoprotein (LDL) cholesterol from circulation.
By regulating the levels of SREBP2, another protein linked to cholesterol control, embelin ultimately enhances the liver's capacity to clear LDL from the bloodstream. This mechanism reveals that calcium plays an important role, particularly in how embelin mediates cholesterol levels through its effects on proteins involved in cholesterol metabolism.
Overall, the findings suggest that embelin may offer a natural avenue for improving cholesterol management, particularly in the context of cardiovascular health.
Read More
Most Useful Reviews
9
Aids sleep quality
It smells a bit funky, yet tastes good and improves my sleep! This high-quality valerian root requires very little for a restful night. During my first preparation, my children thought someone was wearing smelly socks! However, the taste is not as unpleasant as the odour; adding a nice herbal blend enhances the flavour. It’s very effective, but I wouldn’t recommend using it for more than three nights consecutively - it's that potent!
Read More
7.5
Promotes relaxation
1 people found this helpful
It relaxes me greatly; I truly enjoyed drinking valerian root tea, as I feel much calmer afterwards. It's of high quality, and I love it.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
- All Researches
9
We examined the effects of embelin, a compound derived from the dried berries of Embelia ribes, on cholesterol levels by focusing on its relationship with calcium in liver cells. Our analysis showed that embelin treatment aids in regulating cholesterol metabolism by influencing key proteins associated with cholesterol clearance.
The study highlighted how embelin can elevate calcium levels within the endoplasmic reticulum (ER), which is essential for proper cellular function. By increasing calcium, we observed a decrease in the activity of a protein known as PCSK9, which typically hinders the liver's ability to remove low-density lipoprotein (LDL) cholesterol from circulation.
By regulating the levels of SREBP2, another protein linked to cholesterol control, embelin ultimately enhances the liver's capacity to clear LDL from the bloodstream. This mechanism reveals that calcium plays an important role, particularly in how embelin mediates cholesterol levels through its effects on proteins involved in cholesterol metabolism.
Overall, the findings suggest that embelin may offer a natural avenue for improving cholesterol management, particularly in the context of cardiovascular health.
The study highlighted how embelin can elevate calcium levels within the endoplasmic reticulum (ER), which is essential for proper cellular function. By increasing calcium, we observed a decrease in the activity of a protein known as PCSK9, which typically hinders the liver's ability to remove low-density lipoprotein (LDL) cholesterol from circulation.
By regulating the levels of SREBP2, another protein linked to cholesterol control, embelin ultimately enhances the liver's capacity to clear LDL from the bloodstream. This mechanism reveals that calcium plays an important role, particularly in how embelin mediates cholesterol levels through its effects on proteins involved in cholesterol metabolism.
Overall, the findings suggest that embelin may offer a natural avenue for improving cholesterol management, particularly in the context of cardiovascular health.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Aids sleep quality
It smells a bit funky, yet tastes good and improves my sleep! This high-quality valerian root requires very little for a restful night. During my first preparation, my children thought someone was wearing smelly socks! However, the taste is not as unpleasant as the odour; adding a nice herbal blend enhances the flavour. It’s very effective, but I wouldn’t recommend using it for more than three nights consecutively - it's that potent!
Read More
7.5
Promotes relaxation
1 people found this helpful
It relaxes me greatly; I truly enjoyed drinking valerian root tea, as I feel much calmer afterwards. It's of high quality, and I love it.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Chandran M, Rameshkumar KB, Jaleel A, Ayyappan JP. Embelin Elevates Endoplasmic Reticulum Calcium Levels and Blocks the Sterol Regulatory Element-Binding Protein 2 Mediated Proprotein Convertase Subtilisin/Kexin Type 9 Expression and Improves the Low-Density Lipoprotein Receptor Mediated Lipid Clearance on Hepatocytes. Chem Biol Drug Des. 2025;105:e70055. 10.1111/cbdd.70055
